Germline Variation Controls the Architecture of Somatic Alterations in Tumors

Studies have suggested that somatic events in tumors can depend on an individual's constitutional genotype. We used squamous cell carcinomas (SCC) of the skin, which arise in high multiplicity in organ transplant recipients, as a model to compare the pattern of somatic alterations within and ac...

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Detalles Bibliográficos
Autores principales: Dworkin, Amy M., Ridd, Katie, Bautista, Dianne, Allain, Dawn C., Iwenofu, O. Hans, Roy, Ritu, Bastian, Boris C., Toland, Amanda Ewart
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944791/
https://www.ncbi.nlm.nih.gov/pubmed/20885788
http://dx.doi.org/10.1371/journal.pgen.1001136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944791/
https://www.ncbi.nlm.nih.gov/pubmed/20885788
http://dx.doi.org/10.1371/journal.pgen.1001136

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