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Germline Variation Controls the Architecture of Somatic Alterations in Tumors
Studies have suggested that somatic events in tumors can depend on an individual's constitutional genotype. We used squamous cell carcinomas (SCC) of the skin, which arise in high multiplicity in organ transplant recipients, as a model to compare the pattern of somatic alterations within and ac...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944791/ https://www.ncbi.nlm.nih.gov/pubmed/20885788 http://dx.doi.org/10.1371/journal.pgen.1001136 |