Inhibition of Effector Function but Not T Cell Activation and Increase in FoxP3 Expression in T Cells Differentiated in the Presence of PP14

BACKGROUND: T-helper polarization of naïve T cells is determined by a complex mechanism that involves many factors, eventually leading to activation of Th1, Th2, or Th17 responses or alternatively the generation of regulatory T cells. Placental Protein 14 (PP14) is a 28 kDa glycoprotein highly secre...

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Detalles Bibliográficos
Autores principales: Ochanuna, Zohar, Geiger-Maor, Anat, Dembinsky-Vaknin, Adi, Karussis, Dimitrios, Tykocinski, Mark L., Rachmilewitz, Jacob
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944811/
https://www.ncbi.nlm.nih.gov/pubmed/20886106
http://dx.doi.org/10.1371/journal.pone.0012868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944811/
https://www.ncbi.nlm.nih.gov/pubmed/20886106
http://dx.doi.org/10.1371/journal.pone.0012868

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