A Novel System for the Efficient Generation of Antibodies Following Immunization of Unique Knockout Mouse Strains

BACKGROUND: We wished to develop alternate production strategies to generate antibodies against traditionally problematic antigens. As a model we chose butyrylcholinesterase (BChE), involved in termination of cholinergic signaling, and widely considered as a poor immunogen. METHODOLOGY/PRINCIPAL FIN...

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Detalles Bibliográficos
Autores principales: Hrabovska, Anna, Bernard, Véronique, Krejci, Eric
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944837/
https://www.ncbi.nlm.nih.gov/pubmed/20886120
http://dx.doi.org/10.1371/journal.pone.0012892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944837/
https://www.ncbi.nlm.nih.gov/pubmed/20886120
http://dx.doi.org/10.1371/journal.pone.0012892

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