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A Novel System for the Efficient Generation of Antibodies Following Immunization of Unique Knockout Mouse Strains
BACKGROUND: We wished to develop alternate production strategies to generate antibodies against traditionally problematic antigens. As a model we chose butyrylcholinesterase (BChE), involved in termination of cholinergic signaling, and widely considered as a poor immunogen. METHODOLOGY/PRINCIPAL FIN...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944837/ https://www.ncbi.nlm.nih.gov/pubmed/20886120 http://dx.doi.org/10.1371/journal.pone.0012892 |