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EGR-2 Is Not Required for In Vivo CD4 T Cell Mediated Immune Responses

BACKGROUND: The zinc finger transcription factor EGR-2 has been shown to play an important role in the induction of T cell anergy and the regulation of peripheral T cell tolerance. In vitro, a prior study has show that T cells deficient in EGR-2 are hyperproliferative to IL-2 and produce elevated le...

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Detalles Bibliográficos
Autores principales: Ramón, Hilda E., Cejas, Pedro J., LaRosa, David, Rahman, Adeeb, Harris, John E., Zhang, Jidong, Hunter, Christopher, Choi, Yongwon, Turka, Laurence A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944839/
https://www.ncbi.nlm.nih.gov/pubmed/20886122
http://dx.doi.org/10.1371/journal.pone.0012904