Abrogation of E-Cadherin-Mediated Cellular Aggregation Allows Proliferation of Pluripotent Mouse Embryonic Stem Cells in Shake Flask Bioreactors

BACKGROUND: A fundamental requirement for the exploitation of embryonic stem (ES) cells in regenerative medicine is the ability to reproducibly derive sufficient numbers of cells of a consistent quality in a cost-effective manner. However, undifferentiated ES cells are not ideally suited to suspensi...

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Detalles Bibliográficos
Autores principales: Mohamet, Lisa, Lea, Michelle L., Ward, Christopher M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944850/
https://www.ncbi.nlm.nih.gov/pubmed/20886069
http://dx.doi.org/10.1371/journal.pone.0012921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944850/
https://www.ncbi.nlm.nih.gov/pubmed/20886069
http://dx.doi.org/10.1371/journal.pone.0012921

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