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Abrogation of E-Cadherin-Mediated Cellular Aggregation Allows Proliferation of Pluripotent Mouse Embryonic Stem Cells in Shake Flask Bioreactors

BACKGROUND: A fundamental requirement for the exploitation of embryonic stem (ES) cells in regenerative medicine is the ability to reproducibly derive sufficient numbers of cells of a consistent quality in a cost-effective manner. However, undifferentiated ES cells are not ideally suited to suspensi...

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Detalles Bibliográficos
Autores principales:	Mohamet, Lisa, Lea, Michelle L., Ward, Christopher M.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944850/ https://www.ncbi.nlm.nih.gov/pubmed/20886069 http://dx.doi.org/10.1371/journal.pone.0012921

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