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A New Splice Variant of the Major Subunit of Human Asialoglycoprotein Receptor Encodes a Secreted Form in Hepatocytes

BACKGROUND: The human asialoglycoprotein receptor (ASGPR) is composed of two polypeptides, designated H1 and H2. While variants of H2 have been known for decades, the existence of H1 variants has never been reported. PRINCIPAL FINDINGS: We identified two splice variants of ASGPR H1 transcripts, desi...

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Detalles Bibliográficos
Autores principales: Liu, Jia, Hu, Bin, Yang, Yan, Ma, Zhiyong, Yu, Yuan, Liu, Shenpei, Wang, Baoju, Zhao, Xiping, Lu, Mengji, Yang, Dongliang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944864/
https://www.ncbi.nlm.nih.gov/pubmed/20886072
http://dx.doi.org/10.1371/journal.pone.0012934