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Dendritic Cells Reveal a Broad Range of MHC Class I Epitopes for HIV-1 in Persons with Suppressed Viral Load on Antiretroviral Therapy

BACKGROUND: HIV-1 remains sequestered during antiretroviral therapy (ART) and can resume high-level replication upon cessation of ART or development of drug resistance. Reactivity of memory CD8(+) T lymphocytes to HIV-1 could potentially inhibit this residual viral replication, but is largely muted...

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Detalles Bibliográficos
Autores principales: Huang, Xiao-Li, Fan, Zheng, Borowski, LuAnn, Mailliard, Robbie B., Rolland, Morgane, Mullins, James I., Day, Richard D., Rinaldo, Charles R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944894/
https://www.ncbi.nlm.nih.gov/pubmed/20886040
http://dx.doi.org/10.1371/journal.pone.0012936