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Genetics Talks to Epigenetics? The Interplay Between Sequence Variants and Chromatin Structure

Transcription is regulated by two major mechanisms. On the one hand, changes in DNA sequence are responsible for genetic gene regulation. On the other hand, chromatin structure regulates gene activity at the epigenetic level. Given the fundamental participation of these mechanisms in transcriptional...

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Detalles Bibliográficos
Autores principales: Zaina, Silvio, Pérez-Luque, Elva L, Lund, Gertrud
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945002/
https://www.ncbi.nlm.nih.gov/pubmed/21286314
http://dx.doi.org/10.2174/138920210791616662