Differential effects of locally and systemically administered soluble glycoprotein 130 on pain and inflammation in experimental arthritis

INTRODUCTION: Interleukin-6 (IL-6) is a key player in systemic arthritis, involved in inflammation and joint destruction. IL-6 signalling has also been revealed in nerve cells. Recently, IL-6 and in particular IL-6 together with its soluble IL-6 receptor (sIL-6R) were shown to induce a long-lasting...

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Detalles Bibliográficos
Autores principales: Boettger, Michael K, Leuchtweis, Johannes, Kümmel, Diana, Gajda, Mieczyslaw, Bräuer, Rolf, Schaible, Hans-Georg
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945031/
https://www.ncbi.nlm.nih.gov/pubmed/20626857
http://dx.doi.org/10.1186/ar3079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945031/
https://www.ncbi.nlm.nih.gov/pubmed/20626857
http://dx.doi.org/10.1186/ar3079

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