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Liposomal encapsulation enhances and prolongs the anti-inflammatory effects of water-soluble dexamethasone phosphate in experimental adjuvant arthritis

INTRODUCTION: The objective of this study was to evaluate the efficacy of intravenous (i.v.) injection of liposomally encapsulated dexamethasone phosphate (DxM-P) in comparison to free DxM-P in rats with established adjuvant arthritis (AA). This study focused on polyethylene glycol (PEG)-free liposo...

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Detalles Bibliográficos
Autores principales: Anderson, Rebecca, Franch, Angels, Castell, Margarida, Perez-Cano, Francisco J, Bräuer, Rolf, Pohlers, Dirk, Gajda, Mieczyslaw, Siskos, Alexandros P, Katsila, Theodora, Tamvakopoulos, Constantin, Rauchhaus, Una, Panzner, Steffen, Kinne, Raimund W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945041/
https://www.ncbi.nlm.nih.gov/pubmed/20642832
http://dx.doi.org/10.1186/ar3089