Cargando…
Liposomal encapsulation enhances and prolongs the anti-inflammatory effects of water-soluble dexamethasone phosphate in experimental adjuvant arthritis
INTRODUCTION: The objective of this study was to evaluate the efficacy of intravenous (i.v.) injection of liposomally encapsulated dexamethasone phosphate (DxM-P) in comparison to free DxM-P in rats with established adjuvant arthritis (AA). This study focused on polyethylene glycol (PEG)-free liposo...
Autores principales: | Anderson, Rebecca, Franch, Angels, Castell, Margarida, Perez-Cano, Francisco J, Bräuer, Rolf, Pohlers, Dirk, Gajda, Mieczyslaw, Siskos, Alexandros P, Katsila, Theodora, Tamvakopoulos, Constantin, Rauchhaus, Una, Panzner, Steffen, Kinne, Raimund W |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945041/ https://www.ncbi.nlm.nih.gov/pubmed/20642832 http://dx.doi.org/10.1186/ar3089 |
Ejemplares similares
-
Separating therapeutic efficacy from glucocorticoid side-effects in rodent arthritis using novel, liposomal delivery of dexamethasone phosphate: long-term suppression of arthritis facilitates interval treatment
por: Rauchhaus, Una, et al.
Publicado: (2009) -
Differential clinical efficacy of anti-CD4 monoclonal antibodies in rat adjuvant arthritis is paralleled by differential influence on NF-κB binding activity and TNF-α secretion of T cells
por: Pohlers, Dirk, et al.
Publicado: (2002) -
Expression of cytokine mRNA and protein in joints and lymphoid organs during the course of rat antigen-induced arthritis
por: Pohlers, Dirk, et al.
Publicado: (2005) -
In vitro model for the analysis of synovial fibroblast-mediated degradation of intact cartilage
por: Pretzel, David, et al.
Publicado: (2009) -
The Suckling Rat as a Model for Immunonutrition Studies in Early Life
por: Pérez-Cano, Francisco J., et al.
Publicado: (2012)