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Could the expression of CD86 and FcγRIIB on B cells be functionally related and involved in driving rheumatoid arthritis?

Aberrant immune responses play a pivotal role in the processes that cause inflammation and joint damage in patients with rheumatoid arthritis (RA). Polyclonal B cell activation and the production of autoantibodies are immunological hallmarks of the disease. However, controversy surrounds the pathoge...

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Detalles Bibliográficos
Autores principales: Mauri, Claudia, Jury, Elizabeth C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945044/
https://www.ncbi.nlm.nih.gov/pubmed/20735866
http://dx.doi.org/10.1186/ar3092