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Upregulation of the pro-apoptotic genes BID and FAS in septic shock patients

INTRODUCTION: Lymphocyte apoptosis has been suggested to play a central role in sepsis pathophysiology, and studies in animal models demonstrated that blocking this pathway improves outcome. However, no routine biomarkers of apoptosis are so far available in patients. Thus, the aim of our study was...

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Detalles Bibliográficos
Autores principales: Turrel-Davin, Fanny, Guignant, Caroline, Lepape, Alain, Mougin, Bruno, Monneret, Guillaume, Venet, Fabienne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945101/
https://www.ncbi.nlm.nih.gov/pubmed/20626850
http://dx.doi.org/10.1186/cc9181