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‘Umpolung’ Reactivity in Semiaqueous Amide and Peptide Synthesis

The amide functional group is one of Nature’s key functional and structural elements, most notably within peptides. Amides are also key intermediates in the preparation of a diverse range of therapeutic small molecules. Its construction using available methods focuses principally upon dehydrative ap...

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Detalles Bibliográficos
Autores principales: Shen, Bo, Makley, Dawn M., Johnston, Jeffrey N.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945247/
https://www.ncbi.nlm.nih.gov/pubmed/20577205
http://dx.doi.org/10.1038/nature09125