Cargando…
‘Umpolung’ Reactivity in Semiaqueous Amide and Peptide Synthesis
The amide functional group is one of Nature’s key functional and structural elements, most notably within peptides. Amides are also key intermediates in the preparation of a diverse range of therapeutic small molecules. Its construction using available methods focuses principally upon dehydrative ap...
Autores principales: | Shen, Bo, Makley, Dawn M., Johnston, Jeffrey N. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945247/ https://www.ncbi.nlm.nih.gov/pubmed/20577205 http://dx.doi.org/10.1038/nature09125 |
Ejemplares similares
-
Umpolung Amide Synthesis Using Substoichiometric N-Iodosuccinimide (NIS) and Oxygen as a Terminal
Oxidant
por: Schwieter, Kenneth E., et al.
Publicado: (2014) -
A convergent synthesis of 1,3,4-oxadiazoles from acyl hydrazides under semiaqueous conditions
por: Tokumaru, Kazuyuki, et al.
Publicado: (2017) -
Synthesis of Novel Heterocycles by Amide Activation
and Umpolung Cyclization
por: Zhang, Haoqi, et al.
Publicado: (2020) -
The inverted ketene synthon: a double umpolung approach to enantioselective β(2,3)-amino amide synthesis
por: Vishe, Mahesh, et al.
Publicado: (2018) -
Umpolung strategies for the functionalization of peptides and proteins
por: White, Andrew M., et al.
Publicado: (2022)