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Tetracycline Regulator Expression Alters the Transcriptional Program of Mammalian Cells

BACKGROUND: Tetracycline regulated ectopic gene expression is a widely used tool to study gene function. However, the tetracycline regulator (tetR) itself has been reported to cause certain phenotypic changes in mammalian cells. We, therefore, asked whether human myeloid U937 cells expressing the te...

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Detalles Bibliográficos
Autores principales: Hackl, Hubert, Rommer, Anna, Konrad, Torsten A., Nassimbeni, Christine, Wieser, Rotraud
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945318/
https://www.ncbi.nlm.nih.gov/pubmed/20886048
http://dx.doi.org/10.1371/journal.pone.0013013