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BAMBI Is Expressed in Endothelial Cells and Is Regulated by Lysosomal/Autolysosomal Degradation

BACKGROUND: BAMBI (BMP and Activin Membrane Bound Inhibitor) is considered to influence TGFβ and Wnt signaling, and thereby fibrosis. Surprisingly data on cell type-specific expression of BAMBI are not available. We therefore examined the localization, gene regulation, and protein turnover of BAMBI...

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Detalles Bibliográficos
Autores principales: Xavier, Sandhya, Gilbert, Victoria, Rastaldi, Maria Pia, Krick, Stefanie, Kollins, Dmitrij, Reddy, Anand, Bottinger, Erwin, Cohen, Clemens D., Schlondorff, Detlef
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945319/
https://www.ncbi.nlm.nih.gov/pubmed/20886049
http://dx.doi.org/10.1371/journal.pone.0012995