Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance

BACKGROUND: In 70-80% of cases, neuromyelitis optica (NMO) is associated with highly specific serum auto-antibodies to aquaporin-4 (termed AQP4-Ab or NMO-IgG). Recent evidence strongly suggests that AQP4-Ab are directly involved in the immunopathogenesis of NMO. OBJECTIVE: To assess the frequency, s...

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Detalles Bibliográficos
Autores principales: Jarius, Sven, Franciotta, Diego, Paul, Friedemann, Ruprecht, Klemens, Bergamaschi, Roberto, Rommer, Paulus S, Reuss, Reinhard, Probst, Christian, Kristoferitsch, Wolfgang, Wandinger, Klaus Peter, Wildemann, Brigitte
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945323/
https://www.ncbi.nlm.nih.gov/pubmed/20825655
http://dx.doi.org/10.1186/1742-2094-7-52

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945323/
https://www.ncbi.nlm.nih.gov/pubmed/20825655
http://dx.doi.org/10.1186/1742-2094-7-52

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