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Hematopoietic stem cells exhibit a specific ABC transporter gene expression profile clearly distinct from other stem cells

BACKGROUND: ATP-binding cassette (ABC) transporters protect cells against unrelated (toxic) substances by pumping them across cell membranes. Earlier we showed that many ABC transporters are highly expressed in hematopoietic stem cells (HSCs) compared to more committed progenitor cells. The ABC tran...

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Detalles Bibliográficos
Autores principales: Tang, Leilei, Bergevoet, Saskia M, Gilissen, Christian, de Witte, Theo, Jansen, Joop H, van der Reijden, Bert A, Raymakers, Reinier AP
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945345/
https://www.ncbi.nlm.nih.gov/pubmed/20836839
http://dx.doi.org/10.1186/1471-2210-10-12