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Human skin retention and penetration of a copper tripeptide in vitro as function of skin layer towards anti-inflammatory therapy

OBJECTIVE AND DESIGN: The skin retention and penetration characteristics of copper applied as glycyl-l-histidyl-l-lysine cuprate diacetate were evaluated in vitro in order to assess the potential for its transdermal delivery as anti-inflammatory agent. MATERIALS AND METHODS: Flow-through diffusion c...

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Detalles Bibliográficos
Autores principales: Hostynek, Jurij J., Dreher, Frank, Maibach, Howard I.
Formato: Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945467/
https://www.ncbi.nlm.nih.gov/pubmed/20703511
http://dx.doi.org/10.1007/s00011-010-0214-4