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State-dependent Inhibition of TRPM2 Channel by Acidic pH

Transient receptor potential melastatin 2 (TRPM2) channel fulfills an important role in oxidative stress signaling in immune and other cells, to which local extracellular acidosis is known to occur under physiological or pathological conditions and impose significant effects on their functions. Here...

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Detalles Bibliográficos
Autores principales: Yang, Wei, Zou, Jie, Xia, Rong, Vaal, Meriel L., Seymour, Victoria A., Luo, Jianhong, Beech, David J., Jiang, Lin-Hua
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945533/
https://www.ncbi.nlm.nih.gov/pubmed/20660597
http://dx.doi.org/10.1074/jbc.M110.139774