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State-dependent Inhibition of TRPM2 Channel by Acidic pH
Transient receptor potential melastatin 2 (TRPM2) channel fulfills an important role in oxidative stress signaling in immune and other cells, to which local extracellular acidosis is known to occur under physiological or pathological conditions and impose significant effects on their functions. Here...
Autores principales: | Yang, Wei, Zou, Jie, Xia, Rong, Vaal, Meriel L., Seymour, Victoria A., Luo, Jianhong, Beech, David J., Jiang, Lin-Hua |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945533/ https://www.ncbi.nlm.nih.gov/pubmed/20660597 http://dx.doi.org/10.1074/jbc.M110.139774 |
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