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Metabolomic Profiling Reveals Biochemical Pathways and Biomarkers Associated with Pathogenesis in Cystic Fibrosis Cells

Cystic fibrosis (CF) is a life-shortening disease caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. To gain an understanding of the epithelial dysfunction associated with CF mutations and discover biomarkers for therapeutics development, untargeted metabolo...

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Detalles Bibliográficos
Autores principales: Wetmore, Diana R., Joseloff, Elizabeth, Pilewski, Joseph, Lee, Douglas P., Lawton, Kay A., Mitchell, Matthew W., Milburn, Michael V., Ryals, John A., Guo, Lining
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945545/
https://www.ncbi.nlm.nih.gov/pubmed/20675369
http://dx.doi.org/10.1074/jbc.M110.140806