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BLM Deficiency Is Not Associated with Sensitivity to Hydroxyurea-Induced Replication Stress

Bloom's syndrome (BS) displays one of the strongest known correlations between chromosomal instability and a high risk of cancer at an early age. BS cells combine a reduced average fork velocity with constitutive endogenous replication stress. However, the response of BS cells to replication st...

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Detalles Bibliográficos
Autores principales: Lahkim Bennani-Belhaj, Kenza, Buhagiar-Labarchède, Géraldine, Jmari, Nada, Onclercq-Delic, Rosine, Amor-Guéret, Mounira
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945640/
https://www.ncbi.nlm.nih.gov/pubmed/20936166
http://dx.doi.org/10.4061/2010/319754