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Targeting Toll-Like Receptors for Treatment of SLE

Toll-like receptors (TLRs) are important innate immune receptors for the identification and clearance of invading pathogens. Twelve TLRs that recognize various conserved components of microorganisms are currently known. Among these, the endosomal TLRs 3, 7/8, and 9 recognize dsRNA, ssRNA, and CpG DN...

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Detalles Bibliográficos
Autores principales: Horton, Christopher G., Pan, Zi-jian, Farris, A. Darise
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945668/
https://www.ncbi.nlm.nih.gov/pubmed/20886024
http://dx.doi.org/10.1155/2010/498980