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Interactions of Attenuated Mycobacterium tuberculosis phoP Mutant with Human Macrophages
BACKGROUND: Mycobacterium tuberculosis phoP mutant SO2 derived from a clinical isolate was shown to be attenuated in mouse bone marrow-derived macrophages and in vivo mouse infection model and has demonstrated a high potential as attenuated vaccine candidate against tuberculosis. METHODOLOGY/PRINCIP...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945763/ https://www.ncbi.nlm.nih.gov/pubmed/20885976 http://dx.doi.org/10.1371/journal.pone.0012978 |