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TGFβ1 Attenuates Expression of Prolactin and IGFBP-1 in Decidualized Endometrial Stromal Cells by Both SMAD-Dependent and SMAD-Independent Pathways

BACKGROUND: Decidualization (differentiation) of the endometrial stromal cells during the secretory phase of the menstrual cycle is essential for successful implantation. Transforming Growth Factor β1 (TGFβ1) canonically propagates its actions via SMAD signalling. A role for TGFβ1 in decidualization...

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Detalles Bibliográficos
Autores principales: Kane, Nicole M., Jones, Marius, Brosens, Jan J., Kelly, Rodney W., Saunders, Philippa T. K., Critchley, Hilary O. D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945765/
https://www.ncbi.nlm.nih.gov/pubmed/20885978
http://dx.doi.org/10.1371/journal.pone.0012970