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Dosage compensation and the global re-balancing of aneuploid genomes

Diploid genomes are exquisitely balanced systems of gene expression. The dosage-compensation systems that evolved along with monosomic sex chromosomes exemplify the intricacies of compensating for differences in gene copy number by transcriptional regulation.

Detalles Bibliográficos
Autores principales: Prestel, Matthias, Feller, Christian, Becker, Peter B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945780/
https://www.ncbi.nlm.nih.gov/pubmed/20804581
http://dx.doi.org/10.1186/gb-2010-11-8-216