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Differential detection of alternatively spliced variants of Ciz1 in normal and cancer cells using a custom exon-junction microarray

BACKGROUND: Ciz1 promotes initiation of mammalian DNA replication and is present within nuclear matrix associated DNA replication factories. Depletion of Ciz1 from normal and cancer cells restrains entry to S phase and inhibits cell proliferation. Several alternative splicing events with putative fu...

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Detalles Bibliográficos
Autores principales: Rahman, Faisal A, Aziz, Naveed, Coverley, Dawn
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945943/
https://www.ncbi.nlm.nih.gov/pubmed/20831784
http://dx.doi.org/10.1186/1471-2407-10-482