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Differential detection of alternatively spliced variants of Ciz1 in normal and cancer cells using a custom exon-junction microarray
BACKGROUND: Ciz1 promotes initiation of mammalian DNA replication and is present within nuclear matrix associated DNA replication factories. Depletion of Ciz1 from normal and cancer cells restrains entry to S phase and inhibits cell proliferation. Several alternative splicing events with putative fu...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945943/ https://www.ncbi.nlm.nih.gov/pubmed/20831784 http://dx.doi.org/10.1186/1471-2407-10-482 |