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t-DARPP regulates phosphatidylinositol-3-kinase-dependent cell growth in breast cancer
BACKGROUND: Recent reports have shown that t-DARPP (truncated isoform of DARPP-32) can mediate trastuzumab resistance in breast cancer cell models. In this study, we evaluated expression of t-DARPP in human primary breast tumors, and investigated the role of t-DARPP in regulating growth and prolifer...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945963/ https://www.ncbi.nlm.nih.gov/pubmed/20836878 http://dx.doi.org/10.1186/1476-4598-9-240 |