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Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo

BACKGROUND: RhoA and RhoC have been proved to be over-expressed in many solid cancers, including colorectal cancer. The reduction of RhoA and RhoC expression by RNA interference (RNAi) resulted growth inhibition of cancer cells. The present study was to evaluate the effect of silencing of RhoA and R...

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Detalles Bibliográficos
Autores principales: Wang, Haibo, Zhao, Gang, Liu, Xiangping, Sui, Aihua, Yang, Kun, Yao, Ruyong, Wang, Zongbao, Shi, Qiang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945978/
https://www.ncbi.nlm.nih.gov/pubmed/20828398
http://dx.doi.org/10.1186/1756-9966-29-123