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Role of protease-activated receptor-2 on cell death and DNA fragmentation in Helicobacter pylori-infected gastric epithelial cells

BACKGROUND: Helicobacter pylori (H. pylori) infection is associated with chronic gastritis, peptic ulceration and gastric carcinoma. Protease-activated receptor-2 (PAR-2), which is activated by trypsin, induced the activation of mitogen-activated protein kinases (MAPK), cell proliferation and apopto...

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Detalles Bibliográficos
Autores principales: Lim, Joo Weon, Kim, Hyeyoung
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945981/
https://www.ncbi.nlm.nih.gov/pubmed/20846373
http://dx.doi.org/10.1186/1479-5876-8-85