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Lubiprostone ameliorates the cystic fibrosis mouse intestinal phenotype
BACKGROUND: Cystic fibrosis (CF) is caused by mutations in the CFTR gene that impair the function of CFTR, a cAMP-regulated anion channel. In the small intestine loss of CFTR function creates a dehydrated, acidic luminal environment which is believed to cause an accumulation of mucus, a phenotype ch...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945989/ https://www.ncbi.nlm.nih.gov/pubmed/20843337 http://dx.doi.org/10.1186/1471-230X-10-107 |