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Disruption of reducing pathways is not essential for efficient disulfide bond formation in the cytoplasm of E. coli

BACKGROUND: The formation of native disulfide bonds is a complex and essential post-translational modification for many proteins. The large scale production of these proteins can be difficult and depends on targeting the protein to a compartment in which disulfide bond formation naturally occurs, us...

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Detalles Bibliográficos
Autores principales: Hatahet, Feras, Nguyen, Van Dat, Salo, Kirsi EH, Ruddock, Lloyd W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946281/
https://www.ncbi.nlm.nih.gov/pubmed/20836848
http://dx.doi.org/10.1186/1475-2859-9-67