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FATS is a transcriptional target of p53 and associated with antitumor activity

Frequent mutations of p53 in human cancers exemplify its crucial role as a tumor suppressor transcription factor, and p21, a transcriptional target of p53, plays a central role in surveillance of cell-cycle checkpoints. Our previous study has shown that FATS stabilize p21 to preserve genome integrit...

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Detalles Bibliográficos
Autores principales: Zhang, Xifeng, Zhang, Qian, Zhang, Jun, Qiu, Li, Yan, Shuang-shuang, Feng, Juling, Sun, Yan, Huang, Xingxu, Lu, Karen H, Li, Zheng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946289/
https://www.ncbi.nlm.nih.gov/pubmed/20843368
http://dx.doi.org/10.1186/1476-4598-9-244