Anti-angiogenic effects of differentiation-inducing factor-1 involving VEGFR-2 expression inhibition independent of the Wnt/β-catenin signaling pathway

BACKGROUND: Differentiation-inducing factor-1 (DIF-1) is a putative morphogen that induces cell differentiation in Dictyostelium discoideum. DIF-1 inhibits proliferation of various mammalian tumor cells by suppressing the canonical Wnt/β-catenin signaling pathway. To assess the potential of a novel...

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Detalles Bibliográficos
Autores principales: Yoshihara, Tatsuya, Takahashi-Yanaga, Fumi, Shiraishi, Fumie, Morimoto, Sachio, Watanabe, Yutaka, Hirata, Masato, Hoka, Sumio, Sasaguri, Toshiyuki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946290/
https://www.ncbi.nlm.nih.gov/pubmed/20843378
http://dx.doi.org/10.1186/1476-4598-9-245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946290/
https://www.ncbi.nlm.nih.gov/pubmed/20843378
http://dx.doi.org/10.1186/1476-4598-9-245

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