Trop2 expression contributes to tumor pathogenesis by activating the ERK MAPK pathway

BACKGROUND: Trop2 is a cell-surface glycoprotein overexpressed by a variety of epithelial carcinomas with reported low to restricted expression in normal tissues. Expression of Trop2 has been associated with increased tumor aggressiveness, metastasis and decreased patient survival, but the signaling...

Descripción completa

Detalles Bibliográficos
Autores principales: Cubas, Rafael, Zhang, Sheng, Li, Min, Chen, Changyi, Yao, Qizhi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946292/
https://www.ncbi.nlm.nih.gov/pubmed/20858281
http://dx.doi.org/10.1186/1476-4598-9-253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946292/
https://www.ncbi.nlm.nih.gov/pubmed/20858281
http://dx.doi.org/10.1186/1476-4598-9-253

Ejemplares similares