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Highly Specific Antibodies for Co-Detection of Human Choline Kinase α1 and α2 Isoforms

BACKGROUND: Choline kinase is the first enzyme in the CDP-choline pathway that synthesizes phosphatidylcholine, the major phospholipid in eukaryotic cell membranes. In humans, choline kinase exists as three isoforms (CKα1, α2, and β). Specific inhibition of CKα has been reported to selectively kill...

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Detalles Bibliográficos
Autores principales: See Too, Wei Cun, Wong, Mun Teng, Few, Ling Ling, Konrad, Manfred
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946341/
https://www.ncbi.nlm.nih.gov/pubmed/20886003
http://dx.doi.org/10.1371/journal.pone.0012999