SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity via CP110 degradation

Generally, F-box proteins are the substrate recognition subunits of SCF (Skp1-Cul1-F-box protein) ubiquitin ligase complexes, which mediate the timely proteolysis of important eukaryotic regulatory proteins1,2. Mammalian genomes encode roughly 70 F-box proteins, but only a handful have established f...

Descripción completa

Detalles Bibliográficos
Autores principales: D’Angiolella, Vincenzo, Donato, Valerio, Vijayakumar, Sangeetha, Saraf, Anita, Florens, Laurence, Washburn, Michael P., Dynlacht, Brian, Pagano, Michele
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946399/
https://www.ncbi.nlm.nih.gov/pubmed/20596027
http://dx.doi.org/10.1038/nature09140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946399/
https://www.ncbi.nlm.nih.gov/pubmed/20596027
http://dx.doi.org/10.1038/nature09140

Ejemplares similares