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Antigen-Specific B Cells Reactivate an Effective Cytotoxic T Cell Response against Phagocytosed Salmonella through Cross-Presentation

BACKGROUND: The eradication of facultative intracellular bacterial pathogens, like Salmonella typhi, requires the concerted action of both the humoral immune response and the cytotoxic CD8(+) T cell response. Dendritic cells (DCs) are considered to orchestrate the cytotoxic CD8(+) T cell response vi...

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Detalles Bibliográficos
Autores principales: de Wit, Jelle, Souwer, Yuri, Jorritsma, Tineke, Klaasse Bos, Hanny, ten Brinke, Anja, Neefjes, Jacques, van Ham, S. Marieke
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946406/
https://www.ncbi.nlm.nih.gov/pubmed/20885961
http://dx.doi.org/10.1371/journal.pone.0013016