Replication Past the γ-Radiation-Induced Guanine-Thymine Cross-Link G[8,5-Me]T by Human and Yeast DNA Polymerase η

γ-Radiation-induced intrastrand guanine-thymine cross-link, G[8,5-Me]T, hinders replication in vitro and is mutagenic in mammalian cells. Herein we report in vitro translesion synthesis of G[8,5-Me]T by human and yeast DNA polymerase η (hPol η and yPol η). dAMP misincorporation opposite the cross-li...

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Detalles Bibliográficos
Autores principales: Raychaudhury, Paromita, Basu, Ashis K.
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946590/
https://www.ncbi.nlm.nih.gov/pubmed/20936176
http://dx.doi.org/10.4061/2010/101495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946590/
https://www.ncbi.nlm.nih.gov/pubmed/20936176
http://dx.doi.org/10.4061/2010/101495

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