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Expression of a Novel Chimeric Truncated t-PA in CHO Cells Based on in Silico Experiments

Tissue plasminogen activator (t-PA) is one of the fibrin-specific serine proteases that play a crucial role in the fibrinolytic system. The rapid clearance of the drug from the circulation, caused by its active uptake in the liver, has lead to complicated clinical applications. Different forms of pl...

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Detalles Bibliográficos
Autores principales: Davami, Fatemeh, Sardari, Soroush, Majidzadeh-A, Keivan, Hemayatkar, Mehdi, Barkhrdari, Farzaneh, Omidi, Maryam, Azami, Mehrnaz, Adeli, Ahmad, Davoudi, Noushin, Mahboudi, Fereidoun
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946600/
https://www.ncbi.nlm.nih.gov/pubmed/20885932
http://dx.doi.org/10.1155/2010/108159