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Expression of a Novel Chimeric Truncated t-PA in CHO Cells Based on in Silico Experiments
Tissue plasminogen activator (t-PA) is one of the fibrin-specific serine proteases that play a crucial role in the fibrinolytic system. The rapid clearance of the drug from the circulation, caused by its active uptake in the liver, has lead to complicated clinical applications. Different forms of pl...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946600/ https://www.ncbi.nlm.nih.gov/pubmed/20885932 http://dx.doi.org/10.1155/2010/108159 |