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Stacking and energetic contribution of aromatic islands at the binding interface of antibody proteins

BACKGROUND: The enrichment and importance of some aromatic residues, such as Tyr and Trp, have been widely noticed at the binding interfaces of antibodies from many experimental and statistical results, some of which were even identified as “hot spots” contributing significantly greater to the bindi...

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Detalles Bibliográficos
Autores principales: Wu, Di, Sun, Jing, Xu, Tianlei, Wang, Shuning, Li, Guoqing, Li, Yixue, Cao, Zhiwei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946779/
https://www.ncbi.nlm.nih.gov/pubmed/20875152
http://dx.doi.org/10.1186/1745-7580-6-S1-S1