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Stacking and energetic contribution of aromatic islands at the binding interface of antibody proteins
BACKGROUND: The enrichment and importance of some aromatic residues, such as Tyr and Trp, have been widely noticed at the binding interfaces of antibodies from many experimental and statistical results, some of which were even identified as “hot spots” contributing significantly greater to the bindi...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946779/ https://www.ncbi.nlm.nih.gov/pubmed/20875152 http://dx.doi.org/10.1186/1745-7580-6-S1-S1 |