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Clustering-based identification of clonally-related immunoglobulin gene sequence sets
BACKGROUND: Clonal expansion of B lymphocytes coupled with somatic mutation and antigen selection allow the mammalian humoral immune system to generate highly specific immunoglobulins (IG) or antibodies against invading bacteria, viruses and toxins. The availability of high-throughput DNA sequencing...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946782/ https://www.ncbi.nlm.nih.gov/pubmed/20875155 http://dx.doi.org/10.1186/1745-7580-6-S1-S4 |