Contribution of Amino Acid Region 659−663 of Factor Va Heavy Chain to the Activity of Factor Xa within Prothrombinase,

[Image: see text] Factor Va, the cofactor of prothrombinase, is composed of heavy and light chains associated noncovalently in the presence of divalent metal ions. The COOH-terminal region of the heavy chain contains acidic amino acid clusters that are important for cofactor activity. In this work,...

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Detalles Bibliográficos
Autores principales: Hirbawi, Jamila, Vaughn, John L., Bukys, Michael A., Vos, Hans L., Kalafatis, Michael
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946813/
https://www.ncbi.nlm.nih.gov/pubmed/20722419
http://dx.doi.org/10.1021/bi101097t

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946813/
https://www.ncbi.nlm.nih.gov/pubmed/20722419
http://dx.doi.org/10.1021/bi101097t

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